PILA PHARMA AB

Logotype for PILA PHARMA AB
Ticker/ISIN
PILA
SE0015988274
Marknad/Land
SE
Sweden

Senaste sammanfattade pressmeddelande från PILA PHARMA AB

PILA PHARMA AB, a Swedish biotech company focused on developing TRPV1 inhibitors for treating obesity and diabetes, announced that CEO Gustav H. Gram has increased his shareholding by acquiring 36,677 shares at an average price of SEK 2.26 per share, bringing his total to 167,296 shares. The transaction was reported to the Swedish Financial Supervisory Authority. PILA PHARMA, listed on Nasdaq First North Growth Market, is based in Malmö and owns a TRPV1 asset, including the development candidate XEN-D0501, which has shown promise in treating obesity, type 2 diabetes, and potentially other inflammatory diseases. The company has completed two phase 2a trials demonstrating the safety and potential efficacy of XEN-D0501. It is preparing a new trial to assess the drug's maximal tolerable dose and efficacy in weight reduction. PILA PHARMA also explores licensing opportunities for treating Erythromelalgia and Abdominal Aorta Aneurysm. The company aims to develop XEN-D0501 as a first-in-class oral treatment for obesity and diabetes, addressing significant global health challenges.
PILA PHARMA AB, a Swedish biotech company, has signed a contract with Danish Contract Research Organisation Gubra to demonstrate preclinical proof-of-concept for its drug candidate XEN-D0501 in obese rats. This is part of PILA PHARMA's strategy to develop oral drugs for obesity and diabetes by inhibiting TRPV1. The company completed a rights issue in July to fund these trials, with plans to use proceeds from future warrants to finance clinical trials in humans. The study will involve treating obese male DIO and Zucker rats with XEN-D0501 for four weeks. PILA PHARMA aims to establish proof-of-concept in rats to advance clinical studies in humans. The company has previously completed two phase 2a clinical trials demonstrating the drug's tolerability and efficacy in people with obesity and type 2 diabetes. PILA PHARMA is also exploring licensing opportunities for its drug candidate in other conditions like Erythromelalgia and Abdominal Aorta Aneurysm. Gubra specializes in pre-clinical research and peptide-based drug discovery, with a focus on metabolic and fibrotic diseases.
PILA PHARMA AB, a Swedish biotech company, is developing novel oral drugs based on TRPV1 inhibition for treating obesity and diabetes. The company recently participated in a review of their Half-Year Financial Report with Direkt Studios, where CEO Gustav H. Gram highlighted their low burn-rate, prudent capital allocation, and the successful rights issue to fund obesity studies using their unique TRPV1-inhibitor. PILA PHARMA is financially well-positioned and preparing to initiate studies in obesity. The company's TRPV1 antagonist, XEN-D0501, has shown promise in preclinical and clinical trials for obesity, diabetes, erythromelalgia, and abdominal aorta aneurysm. PILA PHARMA focuses on treatments for obesity, type 2 diabetes, erythromelalgia, and abdominal aorta aneurysm, with ongoing and planned studies to evaluate the efficacy and safety of XEN-D0501. The company is also open to out-licensing opportunities for some projects.
PILA PHARMA AB, a Swedish biotech firm, announced its CEO's participation in a new podcast episode discussing the company's oversubscribed rights issue, which aims to fund the development of a novel TRPV1 inhibitor for obesity studies. The podcast highlights PILA PHARMA's strategy in the growing obesity market and the potential impact of their oral drug solution. The company is advancing its TRPV1 inhibitor, XEN-D0501, through clinical trials for obesity and type 2 diabetes, focusing on safety and efficacy. PILA PHARMA also explores applications for erythromelalgia and abdominal aorta aneurysm, seeking partnerships for further development. The company is listed on Nasdaq First North Growth Market, Sweden.
PILA PHARMA AB, a Swedish biotech company, is developing novel oral drugs based on TRPV1 inhibition for treating obesity and diabetes. The company is hosting a live online event on August 27, 2025, where CEO Gustav H. Gram will discuss the company's Half-Year Financial Report and the outcome of a recent rights issue and directed issue. The event will be streamed live and recorded for later viewing, with opportunities for questions via email or chat. PILA PHARMA is developing the TRPV1 antagonist XEN-D0501, which has shown promise in treating obesity, type 2 diabetes, erythromelalgia, and abdominal aorta aneurysm. The company is preparing for further clinical trials to evaluate the safety and efficacy of XEN-D0501. Obesity and diabetes are significant global health issues, with obesity often leading to type 2 diabetes and associated health complications. Erythromelalgia is a rare disease causing pain and redness, while abdominal aorta aneurysm is a cardiovascular condition with no current preventive treatment. PILA PHARMA is collaborating with Uppsala University on research related to abdominal aorta aneurysm.
PILA PHARMA AB announced the completion of a rights issue of units, which included shares and warrants, as well as additional directed issues to underwriters. This process increased the company's total shares by 14,957,792 and its share capital by SEK 639,537.411461, resulting in a dilution effect of approximately 55.14%. The warrants issued allow holders to subscribe for additional shares at a later date, potentially increasing the total share count further. PILA PHARMA is a Swedish biotech company focused on developing TRPV1 antagonists for treating obesity and type 2 diabetes, with ongoing clinical trials and research collaborations. The company also explores treatments for erythromelalgia and abdominal aorta aneurism. The press release includes legal disclaimers about distribution restrictions and forward-looking statements.
PILA PHARMA AB, a Swedish biotech company, announced that the last day for trading in paid subscribed units related to its rights issue is expected to be on August 5, 2025. The new shares are anticipated to begin trading on Nasdaq First North Growth Market on August 11, 2025. PILA PHARMA focuses on developing TRPV1 antagonists, including XEN-D0501, for treating obesity and type 2 diabetes. The company has completed two phase 2a clinical trials indicating the compound's safety and efficacy. Future plans include further clinical trials and potential treatments for erythromelalgia and abdominal aorta aneurism. The company is involved in a research collaboration with Uppsala University and has received orphan drug designation for XEN-D0501. Legal restrictions apply to the distribution of this press release in certain jurisdictions, and it does not constitute an offer for securities. The announcement includes forward-looking statements subject to risks and uncertainties.
PILA PHARMA AB has completed a rights issue of units, with a directed issue of 487,500 units to underwriters as compensation, priced at SEK 2.00 per unit. This aims to fulfill contractual obligations and improve the company's financial position. The Compensation Issue will increase the number of shares by 487,500 and the share capital by SEK 20,843.617032, resulting in a 1.2% dilution effect. If all warrants are exercised, the number of shares will further increase by 975,000, leading to a 1.4% total dilution effect. The warrants allow subscription for new shares between February 5-15, 2026, at a price between SEK 1.50 and SEK 3.00 per share. PILA PHARMA is a Swedish biotech company focused on developing treatments for obesity, type 2 diabetes, erythromelalgia, and abdominal aorta aneurism, with its candidate XEN-D0501 showing promising results. The press release includes legal restrictions on its distribution and emphasizes the forward-looking nature of the statements.

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Press Release: KALLELSE TILL ÅRSSTÄMMA I PILA PHARMA AB

Aktieägarna i PILA PHARMA AB kallas till årsstämma den 29 april 2025 i Malmö. För att delta måste aktieägare vara registrerade i aktieboken senast den 17 april och anmäla sig senast den 23 april. Vid stämman kommer olika ärenden att behandlas, inklusive godkännande av årsredovisningen, beslut om vinstdisposition och ansvarsfrihet för styrelsen. Valberedningen föreslår omval av styrelseledamöter och revisor. Styrelsen föreslår att ingen utdelning lämnas för 2024 och begär bemyndigande att emittera nya aktier. Handlingar inför stämman finns tillgängliga på bolagets huvudkontor och hemsida. Personuppgifter hanteras enligt dataskyddsförordningen.

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Press Release: PILA PHARMA INVITES TO H2 REPORT WEBINAR & INVESTOR Q&A

PILA PHARMA AB is inviting investors to an online webinar on February 27, 2025, where CEO Gustav H. Gram will discuss the company's 2024 second half-year report and their TRPV1 antagonist for obesity and related disorders. The company, listed on Nasdaq First North Growth Market, is a Swedish biotech firm focusing on developing TRPV1 antagonists as treatments for type 2 diabetes, obesity, and other inflammatory diseases. Their lead compound, XEN-D0501, has shown promise in clinical trials for obesity and type 2 diabetes, and has been granted orphan drug designation for erythromelalgia. PILA PHARMA is also exploring its use for abdominal aorta aneurysm, with preclinical success in reducing aneurysm growth in mice. The company is preparing for further clinical trials to assess safety and efficacy in these conditions.

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Press Release: PILA PHARMA ANNOUNCES PRECLINICAL PROOF-OF-CONCEPT ACHIEVED IN CARDIOVASCULAR DISEASE STUDY

PILA PHARMA AB has announced the completion of a study by Professor Dick Wågsäter's Research Group at Uppsala University, which showed that their TRPV1 antagonist, XEN-D0501, significantly reduced the growth of Abdominal Aorta Aneurysm (AAA) in mice. This establishes a preclinical proof-of-concept for the drug's potential to reduce chronic inflammation leading to cardiovascular diseases, including aorta dilatation. The study revealed that XEN-D0501 decreased aorta dilatation by over 50% compared to placebo, nearly inhibiting aneurysm development in the model. The results await further validation before publication. PILA PHARMA focuses on developing TRPV1 antagonists for type 2 diabetes and other inflammatory diseases. XEN-D0501 has shown good safety profiles in previous trials and is being prepared for further clinical studies. The company also holds patents for using TRPV1 antagonists in treating obesity and diabetes. PILA PHARMA is based in Malmö, Sweden, and is listed on the Nasdaq First North Growth Market.

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Press Release: PILA PHARMA ANNOUNCES NEW CHIEF FINANCIAL OFFICER (CFO)

PILA PHARMA AB has appointed Hampus Darrell as its new Chief Financial Officer (CFO). Hampus brings extensive experience in accounting and financial management, having worked in various roles at KPMG and E.ON, and as CFO at Setterwalls Advokatbyrå. He holds a Master of Science in Business and Economics from Lund University and became a Swedish Certified Public Accountant in 2005. Hampus will join PILA PHARMA part-time from December 2024, succeeding Elna Lembrér Åström, who is retiring. PILA PHARMA, a Swedish biotech company, focuses on developing TRPV1 antagonists for treating type 2 diabetes and other inflammatory diseases. The company owns the development candidate XEN-D0501, which has shown promise in clinical trials. PILA PHARMA is working on projects related to type 2 diabetes, erythromelalgia, and abdominal aorta aneurism. The company also collaborates with Uppsala University to study the effects of XEN-D0501 on abdominal aorta aneurism growth in mice.

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Press Release: PILA PHARMA ANNOUNCES INITIATION OF STUDY IN PRECLINICAL RESEARCH COLLABORATION IN CARDIOVASCULAR DISEASE

PILA PHARMA AB has announced the start of a study in collaboration with Professor Dick Wågsäter's research group at Uppsala University. The study aims to investigate the effects of PILA PHARMA's lead molecule, XEN-D0501, on the growth of Abdominal Aorta Aneurism (AAA) in mice. The hypothesis is that XEN-D0501 may reduce inflammation leading to cardiovascular diseases, potentially preventing AAA's progression. PILA PHARMA will co-sponsor the research, with the Research Group retaining publication rights after patenting. If successful, this study could lead to human trials. PILA PHARMA, a Swedish biotech company, focuses on developing TRPV1 antagonists for type 2 diabetes and other inflammatory diseases. XEN-D0501 has shown promise in previous trials for diabetes and obesity, and the company is planning further clinical trials to explore its potential benefits.

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Press Release: PILA PHARMA INVITES TO NORDIC INVESTOR MEETINGS

PILA PHARMA AB, a Swedish biotech company, invites investors to several upcoming Nordic events where CEO Gustav H. Gram will discuss the company's innovative treatment for metabolic disorders. The company focuses on developing TRPV1 antagonists, particularly XEN-D0501, for conditions like type 2 diabetes, obesity, and erythromelalgia. XEN-D0501 has shown promise in clinical trials, improving insulin response and reducing cardiovascular biomarkers. The company plans further trials to assess safety and efficacy. PILA PHARMA also explores treatments for erythromelalgia and abdominal aorta aneurism, collaborating on preclinical studies to investigate XEN-D0501's potential effects. Diabetes and obesity are highlighted as significant global health issues, with obesity linked to increased risk of type 2 diabetes and cardiovascular diseases. The company's shares are traded on Nasdaq First North Growth Market in Sweden.

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Press Release: PILA PHARMA AB Chairman & CEO increase their holdings

PILA PHARMA AB (publ) announced that its Chairman of the Board, Dorte X. Gram, and CEO, Gustav H. Gram, have purchased additional shares in the company. Dorte X. Gram, along with Gustav H. Gram, acquired 20,000 shares through their family investment vehicle, Gram Equity Invest AB, at an average price of SEK 4.99. Dorte X. Gram's total holdings now amount to 5,215,086 shares. Separately, Gustav H. Gram privately acquired 11,072 shares on November 15 and 5,914 shares on November 18, at an average price of SEK 4.58, bringing his total holdings to 96,802 shares. Both leaders expressed confidence in the company's potential, particularly in developing TRPV1 antagonists for treating metabolic diseases such as obesity, diabetes, and cardiovascular disease. PILA PHARMA is a Swedish biotech company focusing on developing these antagonists as novel treatments for type 2 diabetes and other inflammatory diseases. The company owns the TRPV1 asset XEN-D0501, which has shown promise in clinical trials. PILA PHARMA is also involved in projects related to erythromelalgia and abdominal aorta aneurism, with ongoing research and development efforts.

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Press Release: PILA PHARMA TO PARTICIPATE IN DANISH INVESTMENT PODCAST "MILLIONÆRKLUBBEN"

PILA PHARMA AB (publ) invites viewers to watch or listen to a broadcast of "Millionærklubben," featuring CEO Gustav H. Gram. He will discuss the company's innovative pill treatment for diabetes, obesity, and other metabolic disorders. The episode is in Danish and will be available on PILA PHARMA's digital platforms. PILA PHARMA is a Swedish biotech firm focused on developing TRPV1 antagonists, particularly XEN-D0501, for treating type 2 diabetes and other conditions. The company has completed two phase 2a clinical trials showing XEN-D0501 is well tolerated and enhances insulin response. Future plans include further trials to assess the safety and efficacy of the drug. PILA PHARMA is also exploring treatments for erythromelalgia and abdominal aorta aneurism. The company collaborates with Uppsala University to study XEN-D0501's effects on aneurism growth in mice.

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Press Release: PILA PHARMA ANNOUNCES SELECTION OF CLINICAL TRIAL SITE AND DECISION TO SEEK SCIENTIFIC ADVICE FOR OPTIMIZED PP-CT03 STUDY DESIGN

PILA PHARMA AB has announced the selection of Professor Mark Evans as the principal investigator and Cambridge University Hospital as the main clinical trial site for their study PP-CT03. The decision follows changes to the trial plan due to safety concerns with non-hospital sites. PILA PHARMA will seek scientific advice from the UK MHRA to enhance the study design for their TRPV1 antagonist, XEN-D0501, aimed at treating diabetes and obesity. The company aims to optimize study efficacy and regulatory approval chances. Despite potential delays, they expect to receive scientific feedback in early 2025. PILA PHARMA focuses on developing treatments for type 2 diabetes, obesity, erythromelalgia, and abdominal aorta aneurism. Their lead molecule, XEN-D0501, has shown promise in previous trials and is being further developed for its potential benefits in metabolic diseases.

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Press Release: PILA PHARMA ANNOUNCES PROGRESSION AND CO-SPONSORSHIP OF PRECLINICAL RESEARCH COLLABORATION IN CARDIOVASCULAR DISEASE

PILA PHARMA AB announced a co-sponsorship with Professor Dick Wågsäter's Research Group at Uppsala University to study the effects of their lead molecule, XEN-D0501, on Abdominal Aorta Aneurism (AAA) growth in mice. The research, supported by approximately SEK 150,000, aims to establish a pre-clinical proof-of-concept that XEN-D0501 could potentially prevent the progression of AAA by reducing chronic inflammation. PILA PHARMA will co-sponsor the project and will obtain patent rights in exchange for sponsoring any resulting patents. The study could pave the way for assessing the molecule's effects in humans if successful. PILA PHARMA, a Swedish biotech company, focuses on developing TRPV1 antagonists for various conditions, including type 2 diabetes, obesity, erythromelalgia, and AAA. XEN-D0501 has shown promise in previous trials for its safety and efficacy in enhancing insulin response and reducing cardiovascular biomarkers. The collaboration with Professor Wågsäter addresses a significant unmet need for AAA treatment, which currently lacks preventive options.

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