PILA PHARMA AB

Logotype for PILA PHARMA AB
Ticker/ISIN
PILA
SE0015988274
Marknad/Land
SE
Sweden

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PILA PHARMA AB, a Swedish biotech company focused on developing TRPV1 inhibitors for treating obesity and diabetes, announced that CEO Gustav H. Gram has increased his shareholding by acquiring 36,677 shares at an average price of SEK 2.26 per share, bringing his total to 167,296 shares. The transaction was reported to the Swedish Financial Supervisory Authority. PILA PHARMA, listed on Nasdaq First North Growth Market, is based in Malmö and owns a TRPV1 asset, including the development candidate XEN-D0501, which has shown promise in treating obesity, type 2 diabetes, and potentially other inflammatory diseases. The company has completed two phase 2a trials demonstrating the safety and potential efficacy of XEN-D0501. It is preparing a new trial to assess the drug's maximal tolerable dose and efficacy in weight reduction. PILA PHARMA also explores licensing opportunities for treating Erythromelalgia and Abdominal Aorta Aneurysm. The company aims to develop XEN-D0501 as a first-in-class oral treatment for obesity and diabetes, addressing significant global health challenges.
PILA PHARMA AB, a Swedish biotech company, has signed a contract with Danish Contract Research Organisation Gubra to demonstrate preclinical proof-of-concept for its drug candidate XEN-D0501 in obese rats. This is part of PILA PHARMA's strategy to develop oral drugs for obesity and diabetes by inhibiting TRPV1. The company completed a rights issue in July to fund these trials, with plans to use proceeds from future warrants to finance clinical trials in humans. The study will involve treating obese male DIO and Zucker rats with XEN-D0501 for four weeks. PILA PHARMA aims to establish proof-of-concept in rats to advance clinical studies in humans. The company has previously completed two phase 2a clinical trials demonstrating the drug's tolerability and efficacy in people with obesity and type 2 diabetes. PILA PHARMA is also exploring licensing opportunities for its drug candidate in other conditions like Erythromelalgia and Abdominal Aorta Aneurysm. Gubra specializes in pre-clinical research and peptide-based drug discovery, with a focus on metabolic and fibrotic diseases.
PILA PHARMA AB, a Swedish biotech company, is developing novel oral drugs based on TRPV1 inhibition for treating obesity and diabetes. The company recently participated in a review of their Half-Year Financial Report with Direkt Studios, where CEO Gustav H. Gram highlighted their low burn-rate, prudent capital allocation, and the successful rights issue to fund obesity studies using their unique TRPV1-inhibitor. PILA PHARMA is financially well-positioned and preparing to initiate studies in obesity. The company's TRPV1 antagonist, XEN-D0501, has shown promise in preclinical and clinical trials for obesity, diabetes, erythromelalgia, and abdominal aorta aneurysm. PILA PHARMA focuses on treatments for obesity, type 2 diabetes, erythromelalgia, and abdominal aorta aneurysm, with ongoing and planned studies to evaluate the efficacy and safety of XEN-D0501. The company is also open to out-licensing opportunities for some projects.
PILA PHARMA AB, a Swedish biotech firm, announced its CEO's participation in a new podcast episode discussing the company's oversubscribed rights issue, which aims to fund the development of a novel TRPV1 inhibitor for obesity studies. The podcast highlights PILA PHARMA's strategy in the growing obesity market and the potential impact of their oral drug solution. The company is advancing its TRPV1 inhibitor, XEN-D0501, through clinical trials for obesity and type 2 diabetes, focusing on safety and efficacy. PILA PHARMA also explores applications for erythromelalgia and abdominal aorta aneurysm, seeking partnerships for further development. The company is listed on Nasdaq First North Growth Market, Sweden.
PILA PHARMA AB, a Swedish biotech company, is developing novel oral drugs based on TRPV1 inhibition for treating obesity and diabetes. The company is hosting a live online event on August 27, 2025, where CEO Gustav H. Gram will discuss the company's Half-Year Financial Report and the outcome of a recent rights issue and directed issue. The event will be streamed live and recorded for later viewing, with opportunities for questions via email or chat. PILA PHARMA is developing the TRPV1 antagonist XEN-D0501, which has shown promise in treating obesity, type 2 diabetes, erythromelalgia, and abdominal aorta aneurysm. The company is preparing for further clinical trials to evaluate the safety and efficacy of XEN-D0501. Obesity and diabetes are significant global health issues, with obesity often leading to type 2 diabetes and associated health complications. Erythromelalgia is a rare disease causing pain and redness, while abdominal aorta aneurysm is a cardiovascular condition with no current preventive treatment. PILA PHARMA is collaborating with Uppsala University on research related to abdominal aorta aneurysm.
PILA PHARMA AB announced the completion of a rights issue of units, which included shares and warrants, as well as additional directed issues to underwriters. This process increased the company's total shares by 14,957,792 and its share capital by SEK 639,537.411461, resulting in a dilution effect of approximately 55.14%. The warrants issued allow holders to subscribe for additional shares at a later date, potentially increasing the total share count further. PILA PHARMA is a Swedish biotech company focused on developing TRPV1 antagonists for treating obesity and type 2 diabetes, with ongoing clinical trials and research collaborations. The company also explores treatments for erythromelalgia and abdominal aorta aneurism. The press release includes legal disclaimers about distribution restrictions and forward-looking statements.
PILA PHARMA AB, a Swedish biotech company, announced that the last day for trading in paid subscribed units related to its rights issue is expected to be on August 5, 2025. The new shares are anticipated to begin trading on Nasdaq First North Growth Market on August 11, 2025. PILA PHARMA focuses on developing TRPV1 antagonists, including XEN-D0501, for treating obesity and type 2 diabetes. The company has completed two phase 2a clinical trials indicating the compound's safety and efficacy. Future plans include further clinical trials and potential treatments for erythromelalgia and abdominal aorta aneurism. The company is involved in a research collaboration with Uppsala University and has received orphan drug designation for XEN-D0501. Legal restrictions apply to the distribution of this press release in certain jurisdictions, and it does not constitute an offer for securities. The announcement includes forward-looking statements subject to risks and uncertainties.
PILA PHARMA AB has completed a rights issue of units, with a directed issue of 487,500 units to underwriters as compensation, priced at SEK 2.00 per unit. This aims to fulfill contractual obligations and improve the company's financial position. The Compensation Issue will increase the number of shares by 487,500 and the share capital by SEK 20,843.617032, resulting in a 1.2% dilution effect. If all warrants are exercised, the number of shares will further increase by 975,000, leading to a 1.4% total dilution effect. The warrants allow subscription for new shares between February 5-15, 2026, at a price between SEK 1.50 and SEK 3.00 per share. PILA PHARMA is a Swedish biotech company focused on developing treatments for obesity, type 2 diabetes, erythromelalgia, and abdominal aorta aneurism, with its candidate XEN-D0501 showing promising results. The press release includes legal restrictions on its distribution and emphasizes the forward-looking nature of the statements.

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Press Release: PILA PHARMA: ALL INVESTOR PRESENTATION RECORDINGS NOW ONLINE

PILA PHARMA AB (publ) is a Swedish biotech company focused on developing TRPV1 antagonists as novel treatments for type 2 diabetes, obesity, and other inflammatory diseases. The company recently shared recordings of presentations by CEO Gustav H. Gram, discussing their lead candidate, XEN-D0501, and its potential in treating obesity and diabetes. XEN-D0501 has shown promise in clinical trials, demonstrating good tolerability and efficacy in enhancing insulin response and reducing cardiovascular biomarkers. The company is preparing for further trials to explore its maximal tolerable dose and efficacy in weight reduction. PILA PHARMA also explores the use of XEN-D0501 for erythromelalgia and abdominal aorta aneurysm, with ongoing research collaborations and plans for proof-of-concept studies. The company aims to address the growing global challenges of obesity and diabetes, which are linked to significant health risks and economic burdens.

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Press Release: PILA PHARMA VISITED DIREKT STUDIOS' INVESTMENT CHANNEL

PILA PHARMA AB, a Swedish biotech company, is developing novel oral drugs targeting the TRPV1 receptor for obesity and diabetes treatment. The company recently participated in an online investment presentation, discussing its approach and the industry's shift towards oral treatment solutions. PILA PHARMA's lead candidate, XEN-D0501, is a TRPV1 antagonist shown to be effective and well-tolerated in early clinical trials for obesity and type 2 diabetes. The company is preparing for further trials to assess the drug's safety and efficacy. Additionally, PILA PHARMA is exploring the use of XEN-D0501 for treating erythromelalgia and abdominal aorta aneurysm, with promising preclinical results. The company holds patents for TRPV1 antagonists and continues to advance its research and development efforts in these areas.

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Press Release: PILA PHARMA PARTICIPATED IN INVESTMENT PODCAST 10X

PILA PHARMA AB, a Swedish biotech company, is developing novel oral drugs based on TRPV1 inhibition for treating obesity and diabetes. CEO Gustav H. Gram discussed the company's goals and the broader market trends, including the 'Longevity' movement, on the 10X podcast. The podcast is available in English, with the PILA segment starting at 33:10. PILA PHARMA is focused on developing TRPV1 antagonists, specifically XEN-D0501, for treating type 2 diabetes and other inflammatory diseases. The company has completed successful phase 2a trials and is preparing for further clinical trials, aiming to identify the maximal tolerable dose and evaluate the safety of XEN-D0501 in people with obesity and type 2 diabetes. The company is also exploring treatments for erythromelalgia and abdominal aorta aneurysm, with promising preclinical results for XEN-D0501 in reducing aneurysm growth in mice. PILA PHARMA's projects are available for out-licensing, and the company continues to advance its research and development efforts.

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Press Release: PILA PHARMA INVITES TO AFTER-WORK MINGLE IN STOCKHOLM

PILA PHARMA AB, a Swedish biotech company focused on developing novel oral drugs for obesity and diabetes using TRPV1 inhibition, is hosting an after-work event on June 11 in Stockholm. The event will feature updates from CEO Gustav H. Gram and Founder Dorte X. Gram on the company's progress and plans, as well as a Q&A session. PILA PHARMA is advancing its development candidate XEN-D0501, a TRPV1 antagonist, which has shown promise in clinical trials for obesity and type 2 diabetes. The company is also exploring its potential for treating erythromelalgia and abdominal aorta aneurysm. PILA PHARMA's shares are traded on Nasdaq First North Growth Market.

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Press Release: PILA PHARMA UPCOMING INVESTOR PRESENTATIONS IN STOCKHOLM

PILA PHARMA AB, a Swedish biotech company, is developing novel oral drugs based on TRPV1 inhibition for treating obesity and diabetes. The company invites investors to several upcoming events where CEO Gustav H. Gram will discuss the company's innovative treatments and market outlook. PILA PHARMA focuses on developing TRPV1 antagonists like XEN-D0501, which have shown potential in treating metabolic disorders. The company has completed two phase 2a trials demonstrating XEN-D0501's safety and efficacy in enhancing insulin response and reducing cardiovascular biomarkers. PILA PHARMA is preparing for a new clinical trial to assess the maximal tolerable dose of XEN-D0501 for obesity and type 2 diabetes. The company also explores treatments for erythromelalgia and abdominal aorta aneurysm, with promising preclinical results for the latter. PILA PHARMA's shares are traded on Nasdaq First North Growth Market, Sweden.

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Press Release: PILA PHARMA DISCUSSED ITS POTENTIAL ROLE IN OBESITY & DIABETES WITH HELGE LARSEN & PROINVESTOR

PILA PHARMA AB, a Swedish biotech company, announced a recent interview with Helge Larsen from ProInvestor, Denmark's largest online forum for investors in biotechnology and pharmaceutical stocks. The interview, conducted in Danish, featured founder and CSO Dorte X. Gram discussing the company's development of a novel oral treatment for obesity and diabetes using a TRPV1 antagonist. The recording is available online, with an English subtitled version forthcoming. PILA PHARMA is listed on Nasdaq First North Growth Market, Sweden, and focuses on developing treatments for obesity, type 2 diabetes, erythromelalgia, and abdominal aorta aneurysm. Their lead candidate, XEN-D0501, has shown promise in clinical trials for improving insulin response and reducing cardiovascular biomarkers. The company is preparing for further clinical trials to assess safety and efficacy. PILA PHARMA also collaborates with Uppsala University on research for abdominal aorta aneurysms, where XEN-D0501 has shown potential in preclinical studies.

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Press Release: PILA PHARMA TO RE-VISIT PROINVESTOR WITH HELGE LARSEN TO DISCUSS THE COMPANY'S AMBITIONS IN OBESITY & DIABETES

PILA PHARMA AB will participate in a 1-on-1 interview with Helge Larsen from ProInvestor on June 5, 2025. The interview will feature Founder and CSO Dorte X. Gram discussing the company's development of a novel oral treatment for obesity and diabetes using a TRPV1 antagonist. The discussion will cover topics such as the mode of action of TRPV1 antagonists, data supporting their use for metabolic diseases, and progress on their lead candidate, XEN-D0501. The interview will be conducted in Danish and transcribed to English, with the recording available on June 6, 2025. PILA PHARMA is a Swedish biotech company focused on developing TRPV1 antagonists for treating type 2 diabetes and other inflammatory diseases. Their lead candidate, XEN-D0501, has shown promising results in clinical trials for obesity and diabetes, and holds orphan drug designation for erythromelalgia. XEN-D0501 has demonstrated efficacy in reducing glucose intolerance and body weight gain in preclinical studies and has a good safety profile. The company is preparing for further clinical trials to assess the safety and efficacy of XEN-D0501. PILA PHARMA is also involved in research for treating erythromelalgia and abdominal aorta aneurysm, with ongoing studies and collaborations to explore the potential of XEN-D0501 in these areas. The company aims to address unmet needs in obesity and diabetes treatment, with a focus on developing accessible oral therapies.

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Press Release: KOMMUNIKÉ FRÅN ÅRSSTÄMMA I PILA PHARMA AB 2025

PILA PHARMA AB held its annual general meeting on April 29, 2025, in Malmö, Sweden, where key decisions were made. The company's financial statements for 2024 were approved, and it was decided that no dividend would be distributed for that year. The board and CEO were granted discharge from liability for 2024. The meeting re-elected board members Dorte Xenia Gram, Richard Busellato, Lasse Richter Petersen, and Julie Waras Brogren, with Dorte Xenia Gram continuing as chair. Deloitte AB was re-elected as auditor, with Maria Ekelund as the lead auditor. The nomination committee will include Dorte Xenia Gram and Niels Raaschou. The board was authorized to issue new shares or financial instruments until the next annual meeting. PILA PHARMA is a Swedish biotech company focused on developing TRPV1 antagonists for treating type 2 diabetes and other inflammatory diseases. Its main asset is XEN-D0501, which has shown promise in clinical trials for obesity and type 2 diabetes. The company plans further trials to determine the maximum tolerable dose and assess safety and efficacy. PILA PHARMA also explores treatments for erythromelalgia and abdominal aorta aneurysm, with ongoing research collaborations and development plans.

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Press Release: PILA PHARMA UPCOMING INVESTOR MEETINGS

PILA PHARMA AB, a Swedish biotech company, invites investors and interested parties to upcoming events where they will present their work on innovative treatments for obesity, diabetes, and other conditions. These events include a panel debate in Malmö on April 28, 2025, the Vator Life Science Summit in Stockholm on May 14, 2025, and the AktieInfo Investor Evening in Copenhagen on May 19, 2025. The company focuses on developing TRPV1 antagonists, specifically XEN-D0501, for treating type 2 diabetes, obesity, erythromelalgia, and abdominal aorta aneurysm. XEN-D0501 has shown promising results in clinical trials, demonstrating good tolerability and efficacy. PILA PHARMA continues to advance its research and development efforts, with plans for further clinical trials and ongoing collaborations. The company is publicly traded on Nasdaq First North Growth Market in Sweden.

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Press Release: PILA PHARMA: REMINDER - LAST DAY FOR SHAREHOLDER REGISTRATION FOR ANNUAL GENERAL MEETING

PILA PHARMA AB (publ) reminds shareholders that April 23 is the last day to register for the Annual General Meeting on April 29, 2025, in Malmö, Sweden. Shareholders can attend in person or vote via proxy. PILA PHARMA, a Swedish biotech company, focuses on developing TRPV1 antagonists for treating type 2 diabetes and other diseases. Their development candidate, XEN-D0501, has shown promise in clinical trials and has potential applications in obesity, diabetes, erythromelalgia, and abdominal aorta aneurysm. The company is preparing for further clinical trials to evaluate safety and efficacy. Obesity and diabetes are significant global health issues, and PILA PHARMA is working on potential treatments for these conditions. Erythromelalgia is a rare disease causing pain and redness, with no current treatments available. Abdominal aorta aneurysm affects many globally, and PILA PHARMA's research has shown potential in reducing its growth.

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