CHOSA Oncology's Gene Test Enhances Cancer Treatment

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CHOSA Oncology's innovative gene test improves treatment decisions for platinum-based chemotherapies.

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Sammanfattning

CHOSA Oncology's patented gene test predicts patient response to platinum-based chemotherapy, enhancing treatment efficacy and reducing toxicity.

CHOSA Oncology, a leading biotechnology company in Sweden, has announced significant advancements in the use of its patented gene test to improve cancer treatment outcomes. This test, which identifies cancer patients most likely to benefit from treatment with platinum-based chemotherapies like cisplatin and carboplatin, now shows promising results in predicting responses to carboplatin as well.

Platinum-based chemotherapies, including cisplatin and carboplatin, are critical in treating various cancers, particularly in advanced stages. Despite their widespread use, these treatments often come with significant toxicity and inconsistent efficacy among patients. CHOSA's gene test, based on a 205-gene Platin-DRP® signature, provides a solution by guiding clinicians in selecting patients who are more likely to respond positively to these treatments.

The test has already been validated for cisplatin in multiple clinical settings, including a prospective phase 2 breast cancer study. The recent evaluation in a cohort of 20 breast cancer patients treated with carboplatin demonstrated statistically significant results, supporting the test's predictive power. This breakthrough has led to CHOSA's submission of an abstract to the European Society for Medical Oncology (ESMO).

CHOSA's innovation not only enhances treatment efficacy but also reduces the risk of exposing patients to ineffective and potentially harmful therapies. By accurately identifying patients who will benefit from platinum-based chemotherapy, healthcare providers can make more informed decisions, ultimately improving patient outcomes.

Given these advancements, CHOSA Oncology presents a compelling case for investors. The company's focus on late-stage clinical development and its strategic partnerships position it well for future growth. Investors should consider holding CHOSA shares as the company continues to validate its gene test across different cancer types and treatment combinations.

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CHOSA submits ESMO abstract on carboplatin response in breast cancer patients

Sammanfattning

Cisplatin and carboplatin are platinum-based chemotherapies used in various cancer treatments, including advanced breast cancer. Their use is often limited due to toxicity and inconsistent patient efficacy. CHOSA holds global rights to a patented gene test, the Cisplatin-DRP®, which identifies patients likely to benefit from these treatments. This test, based on a 205-gene signature, helps guide treatment decisions by predicting patient response to cisplatin and carboplatin, reducing exposure to ineffective therapies. The Cisplatin-DRP® has been validated in clinical trials for cisplatin and recently showed positive results for carboplatin. CHOSA is exploring its use in lung cancer and its potential to predict treatment success with platinum drugs combined with PD-1/L1 inhibitors. The company aims to partner or sublicense its technologies, including LiPlaCis® and the DRP®. The Cisplatin-DRP® has shown promise in improving treatment outcomes for breast and lung cancer patients by identifying those most likely to benefit from cisplatin therapy. Additionally, cisplatin's ability to enhance immune response could provide a competitive edge in the PD-1 inhibitor market.

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